53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function

Class switch recombination (CSR) is a DNA recombination reaction that diversifies the effector functions of antibodies. CSR occurs via the formation and non-homologous end joining (NHEJ) repair of programmed DNA double-strand breaks (DSBs) at the immunoglobulin heavy chain locus. The DNA repair fact...

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Publicado no:Cell Rep
Main Authors: Sundaravinayagam, Devakumar, Rahjouei, Ali, Andreani, Matteo, Tupiņa, Dagnija, Balasubramanian, Sandhya, Saha, Tannishtha, Delgado-Benito, Verónica, Coralluzzo, Violeta, Daumke, Oliver, Di Virgilio, Michela
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693562/
https://ncbi.nlm.nih.gov/pubmed/31390554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.06.035
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