An inherited immunoglobulin class-switch recombination deficiency associated with a defect in the INO80 chromatin remodeling complex

BACKGROUND: Immunoglobulin class-switch recombination defects (CSR-D) are rare primary immunodeficiencies characterized by impaired production of switched immunoglobulin isotypes and normal or elevated IgM levels. They are caused by impaired T:B cooperation or intrinsic B cell defects. However, many...

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Pubblicato in:J Allergy Clin Immunol
Autori principali: Kracker, Sven, Di Virgilio, Michela, Schwartzentruber, Jeremy, Cuenin, Cyrille, Forveille, Monique, Deau, Marie-Céline, McBride, Kevin M., Majewski, Jacek, Gazumyan, Anna, Seneviratne, Suranjith, Grimbacher, Bodo, Kutukculer, Necil, Herceg, Zdenko, Cavazzana, Marina, Jabado, Nada, Nussenzweig, Michel C., Fischer, Alain, Durandy, Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mosby 2015
Soggetti:
Immune Deficiencies, Infection, and Systemic Immune Disorders
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382329/
https://ncbi.nlm.nih.gov/pubmed/25312759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.08.030
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