Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1

53BP1 is a DNA damage protein that forms phosphorylated H2AX (γ-H2AX) dependent foci in a 1 Mb region surrounding DNA double strand breaks (DSBs). In addition, 53BP1 promotes genomic stability by regulating the metabolism of DNA ends. We have compared the joining rates of paired DSBs separated by 1....

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Main Authors: Bothmer, Anne, Robbiani, Davide F., Di Virgilio, Michela, Bunting, Samuel F., Klein, Isaac A., Feldhahn, Niklas, Barlow, Jacqueline, Chen, Henry T., Bosque, David, Callen, Elsa, Nussenzweig, André, Nussenzweig, Michel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142663/
https://ncbi.nlm.nih.gov/pubmed/21549309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.019
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