Regulation of DNA End Joining, Resection, and Immunoglobulin Class Switch Recombination by 53BP1

53BP1 is a DNA damage protein that forms phosphorylated H2AX (γ-H2AX) dependent foci in a 1 Mb region surrounding DNA double strand breaks (DSBs). In addition, 53BP1 promotes genomic stability by regulating the metabolism of DNA ends. We have compared the joining rates of paired DSBs separated by 1....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bothmer, Anne, Robbiani, Davide F., Di Virgilio, Michela, Bunting, Samuel F., Klein, Isaac A., Feldhahn, Niklas, Barlow, Jacqueline, Chen, Henry T., Bosque, David, Callen, Elsa, Nussenzweig, André, Nussenzweig, Michel C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142663/
https://ncbi.nlm.nih.gov/pubmed/21549309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.019
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