Mechanistic insight into ligand binding to G-quadruplex DNA

od Di Leva, Francesco Saverio, Novellino, Ettore, Cavalli, Andrea, Parrinello, Michele, Limongelli, Vittorio
Wydane 2014

Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities

od Cannalire, Rolando, Cerchia, Carmen, Beccari, Andrea R., Di Leva, Francesco Saverio, Summa, Vincenzo
Wydane w J Med Chem (2020)

Bioinformatics and Biosimulations as Toolbox for Peptides and Peptidomimetics Design: Where Are We?

od D’Annessa, Ilda, Di Leva, Francesco Saverio, La Teana, Anna, Novellino, Ettore, Limongelli, Vittorio, Di Marino, Daniele
Wydane w Front Mol Biosci (2020)

Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism

od Di Leva, Francesco Saverio, Festa, Carmen, Renga, Barbara, Sepe, Valentina, Novellino, Ettore, Fiorucci, Stefano, Zampella, Angela, Limongelli, Vittorio
Wydane w Sci Rep (2015)

Click‐Chemistry (CuAAC) Trimerization of an α(v)β(6) Integrin Targeting Ga‐68‐Peptide: Enhanced Contrast for in‐Vivo PET Imaging of Human Lung Adenocarcinoma Xenografts

od Quigley, Neil Gerard, Tomassi, Stefano, di Leva, Francesco Saverio, Di Maro, Salvatore, Richter, Frauke, Steiger, Katja, Kossatz, Susanne, Marinelli, Luciana, Notni, Johannes
Wydane w Chembiochem (2020)

Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties

od Finamore, Claudia, Baronissi, Giuliana, Marchianò, Silvia, Di Leva, Francesco Saverio, Carino, Adriana, Monti, Maria Chiara, Limongelli, Vittorio, Zampella, Angela, Fiorucci, Stefano, Sepe, Valentina
Wydane w Molecules (2019)

Protein Flexibility in Virtual Screening: The BACE-1 Case Study

od Cosconati, Sandro, Marinelli, Luciana, Di Leva, Francesco Saverio, La Pietra, Valeria, De Simone, Angela, Mancini, Francesca, Andrisano, Vincenza, Novellino, Ettore, Goodsell, David S., Olson, Arthur J.
Wydane 2012

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists

od De Marino, Simona, Carino, Adriana, Masullo, Dario, Finamore, Claudia, Marchianò, Silvia, Cipriani, Sabrina, Di Leva, Francesco Saverio, Catalanotti, Bruno, Novellino, Ettore, Limongelli, Vittorio, Fiorucci, Stefano, Zampella, Angela
Wydane w Sci Rep (2017)

Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1

od Di Leva, Francesco Saverio, Festa, Carmen, Carino, Adriana, De Marino, Simona, Marchianò, Silvia, Di Marino, Daniele, Finamore, Claudia, Monti, Maria Chiara, Zampella, Angela, Fiorucci, Stefano, Limongelli, Vittorio
Wydane w Sci Rep (2019)

Investigation around the Oxadiazole Core in the Discovery of a New Chemotype of Potent and Selective FXR Antagonists

od Festa, Carmen, Finamore, Claudia, Marchianò, Silvia, Di Leva, Francesco Saverio, Carino, Adriana, Monti, Maria Chiara, del Gaudio, Federica, Ceccacci, Sara, Limongelli, Vittorio, Zampella, Angela, Fiorucci, Stefano, De Marino, Simona
Wydane w ACS Med Chem Lett (2019)

Identification of Highly Conserved Residues Involved in Inhibition of HIV-1 RNase H Function by Diketo Acid Derivatives

od Corona, Angela, Di Leva, Francesco Saverio, Thierry, Sylvain, Pescatori, Luca, Cuzzucoli Crucitti, Giuliana, Subra, Frederic, Delelis, Olivier, Esposito, Francesca, Rigogliuso, Giuseppe, Costi, Roberta, Cosconati, Sandro, Novellino, Ettore, Di Santo, Roberto, Tramontano, Enzo
Wydane 2014

Marine and Semi-Synthetic Hydroxysteroids as New Scaffolds for Pregnane X Receptor Modulation

od Sepe, Valentina, Di Leva, Francesco Saverio, D’Amore, Claudio, Festa, Carmen, De Marino, Simona, Renga, Barbara, D’Auria, Maria Valeria, Novellino, Ettore, Limongelli, Vittorio, D’Souza, Lisette, Majik, Mahesh, Zampella, Angela, Fiorucci, Stefano
Wydane 2014

Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury

od Sepe, Valentina, Marchianò, Silvia, Finamore, Claudia, Baronissi, Giuliana, Di Leva, Francesco Saverio, Carino, Adriana, Biagioli, Michele, Fiorucci, Chiara, Cassiano, Chiara, Monti, Maria Chiara, del Gaudio, Federica, Novellino, Ettore, Limongelli, Vittorio, Fiorucci, Stefano, Zampella, Angela
Wydane w ACS Med Chem Lett (2018)

GPBAR1 Activation by C6-Substituted Hyodeoxycholane Analogues Protect against Colitis

od Marino, Simona De, Finamore, Claudia, Biagioli, Michele, Carino, Adriana, Marchianò, Silvia, Roselli, Rosalinda, Giorgio, Cristina Di, Bordoni, Martina, Di Leva, Francesco Saverio, Novellino, Ettore, Cassiano, Chiara, Limongelli, Vittorio, Zampella, Angela, Festa, Carmen, Fiorucci, Stefano
Wydane w ACS Med Chem Lett (2020)

Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors

od Taliani, Sabrina, Pugliesi, Isabella, Barresi, Elisabetta, Salerno, Silvia, Marchand, Christophe, Agama, Keli, Simorini, Francesca, La Motta, Concettina, Marini, Anna Maria, Di Leva, Francesco Saverio, Marinelli, Luciana, Cosconati, Sandro, Novellino, Ettore, Pommier, Yves, Di Santo, Roberto, Settimo, Federico Da
Wydane 2013

Halting the Spread of Herpes Simplex Virus-1: The Discovery of an Effective Dual αvβ6/αvβ8 Integrin Ligand

od Tomassi, Stefano, D’Amore, Vincenzo Maria, Di Leva, Francesco Saverio, Vannini, Andrea, Quilici, Giacomo, Weinmüller, Michael, Reichart, Florian, Amato, Jussara, Romano, Barbara, Izzo, Angelo Antonio, Di Maro, Salvatore, Novellino, Ettore, Musco, Giovanna, Gianni, Tatiana, Kessler, Horst, Marinelli, Luciana
Wydane w J Med Chem (2021)

Basic Quinolinonyl Diketo Acid Derivatives as Inhibitors of HIV Integrase and their Activity against RNase H Function of Reverse Transcriptase

od Costi, Roberta, Métifiot, Mathieu, Chung, Suhman, Cuzzucoli Crucitti, Giuliana, Maddali, Kasthuraiah, Pescatori, Luca, Messore, Antonella, Madia, Valentina Noemi, Pupo, Giovanni, Scipione, Luigi, Tortorella, Silvano, Di Leva, Francesco Saverio, Cosconati, Sandro, Marinelli, Luciana, Novellino, Ettore, Le Grice, Stuart F. J., Corona, Angela, Pommier, Yves, Marchand, Christophe, Di Santo, Roberto
Wydane 2014

N-Substituted Quinolinonyl Diketo Acid Derivatives as HIV Integrase Strand Transfer Inhibitors and Their Activity against RNase H Function of Reverse Transcriptase

od Pescatori, Luca, Métifiot, Mathieu, Chung, Suhman, Masoaka, Takashi, Crucitti, Giuliana Cuzzucoli, Messore, Antonella, Pupo, Giovanni, Madia, Valentina Noemi, Saccoliti, Francesco, Scipione, Luigi, Tortorella, Silvano, Di Leva, Francesco Saverio, Cosconati, Sandro, Marinelli, Luciana, Novellino, Ettore, Le Grice, Stuart F. J., Pommier, Yves, Marchand, Christophe, Costi, Roberta, Di Santo, Roberto
Wydane w J Med Chem (2015)