Modification of the DNA Damage Response by Therapeutic CDK4/6 Inhibition

Autor Dean, Jeffry L., McClendon, A. Kathleen, Knudsen, Erik S.
Vydáno 2012

Generation of a novel Wolbachia infection in Aedes albopictus (Asian tiger mosquito) via embryonic microinjection

Autor Xi, Zhiyong, Dean, Jeffry L., Khoo, Cynthia, Dobson, Stephen. L.
Vydáno 2005

Differential Impact of Tumor Suppressor Pathways on DNA Damage Response and Therapy-Induced Transformation in a Mouse Primary Cell Model

Autor McClendon, A. Kathleen, Dean, Jeffry L., Ertel, Adam, Knudsen, Erik S.
Vydáno 2010

Application of Gene Set Enrichment Analysis for Identification of Chemically Induced, Biologically Relevant Transcriptomic Networks and Potential Utilization in Human Health Risk A...

Autor Dean, Jeffry L., Zhao, Q. Jay, Lambert, Jason C., Hawkins, Belinda S., Thomas, Russell S., Wesselkamper, Scott C.
Vydáno v Toxicol Sci (2017)

RB-pathway disruption in breast cancer: Differential association with disease subtypes, disease-specific prognosis and therapeutic response

Autor Ertel, Adam, Dean, Jeffry L, Rui, Hallgeir, Liu, Chengbao, Witkiewicz, Agnes K, Knudsen, Karen E, Knudsen, Erik S
Vydáno 2010

A Case Study on the Application of An Expert-driven Read-Across Approach in Support of Quantitative Risk Assessment of p,p’-Dichlorodiphenyldichloroethane

Autor Lizarraga, Lucina E., Dean, Jeffry L., Kaiser, J. Phillip, Wesselkamper, Scott C., Lambert, Jason C., Zhao, Q. Jay
Vydáno v Regul Toxicol Pharmacol (2019)

Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer

Autor Thangavel, Chellappagounder, Dean, Jeffry L, Ertel, Adam, Knudsen, Karen E, Aldaz, C Marcelo, Witkiewicz, Agnieszka K, Clarke, Robert, Knudsen, Erik S
Vydáno 2011

Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors

Autor Dean, Jeffry L., McClendon, A. Kathleen, Hickey, Theresa E., Butler, Lisa M., Tilley, Wayne D., Witkiewicz, Agnieszka K., Knudsen, Erik S.
Vydáno 2012

CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy

Autor McClendon, A. Kathleen, Dean, Jeffry L., Rivadeneira, Dayana B., Yu, Justine E., Reed, Christopher A., Gao, Erhe, Farber, John L., Force, Thomas, Koch, Walter J., Knudsen, Erik S.
Vydáno 2012

A hormone-DNA repair circuit governs the response to genotoxic insult

Autor Goodwin, Jonathan F., Schiewer, Matthew J., Dean, Jeffry L., Schrecengost, Randy S., de Leeuw, Renee, Han, Sumin, Ma, Teng, Den, Robert B., Dicker, Adam P., Feng, Felix Y., Knudsen, Karen E.
Vydáno 2013

RB and p53 Cooperate to Prevent Liver Tumorigenesis in Response to Tissue Damage

Autor McClendon, A. Kathleen, Dean, Jeffry L., Ertel, Adam, Fu, Zhiyan, Rivadeneira, Dayana B., Reed, Christopher A., Bourgo, Ryan J., Witkiewicz, Agnieszka, Addya, Sankar, Mayhew, Christopher N., Grimes, H. Leighton, Fortina, Paolo, Knudsen, Erik S.
Vydáno v Gastroenterology (2011)

Consequence of the tumor-associated conversion to cyclin D1b

Autor Augello, Michael A, Berman-Booty, Lisa D, Carr, Richard, Yoshida, Akihiro, Dean, Jeffry L, Schiewer, Matthew J, Feng, Felix Y, Tomlins, Scott A, Gao, Erhe, Koch, Walter J, Benovic, Jeffrey L, Diehl, John Alan, Knudsen, Karen E
Vydáno v EMBO Mol Med (2015)

Cyclin D1b Is Aberrantly Regulated in Response to Therapeutic Challenge and Promotes Resistance to Estrogen Antagonists

Autor Wang, Ying, Dean, Jeffry L., Millar, Ewan K.A., Tran, Thai Hong, McNeil, Catriona M., Burd, Craig J., Henshall, Susan M., Utama, Fransiscus E., Witkiewicz, Agnieszka, Rui, Hallgeir, Sutherland, Robert L., Knudsen, Karen E., Knudsen, Erik S.
Vydáno v Cancer Res (2008)

USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression

Autor Schrecengost, Randy S, Dean, Jeffry L, Goodwin, Jonathan F, Schiewer, Matthew J, Urban, Mark W, Stanek, Timothy J, Sussman, Robyn T, Hicks, Jessica L, Birbe, Ruth C, Draganova-Tacheva, Rossitza A, Visakorpi, Tapio, DeMarzo, Angelo M, McMahon, Steven B, Knudsen, Karen E
Vydáno 2013

Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes

Autor Augello, Michael A., Burd, Craig J., Birbe, Ruth, McNair, Christopher, Ertel, Adam, Magee, Michael S., Frigo, Daniel E., Wilder-Romans, Kari, Shilkrut, Mark, Han, Sumin, Jernigan, Danielle L., Dean, Jeffry L., Fatatis, Alessandro, McDonnell, Donald P., Visakorpi, Tapio, Feng, Felix Y., Knudsen, Karen E.
Vydáno 2012

Dual roles of PARP-1 promote cancer growth and progression

Autor Schiewer, Matthew J., Goodwin, Jonathan F., Han, Sumin, Brenner, J. Chad, Augello, Michael A., Dean, Jeffry L., Liu, Fengzhi, Planck, Jamie L., Ravindranathan, Preethi, Chinnaiyan, Arul M., McCue, Peter, Gomella, Leonard G., Raj, Ganesh V., Dicker, Adam P., Brody, Jonathan R., Pascal, John M., Centenera, Margaret M., Butler, Lisa M., Tilley, Wayne D., Feng, Felix Y., Knudsen, Karen E.
Vydáno 2012

RB Loss Promotes Prostate Cancer Metastasis

Autor Thangavel, Chellappagounder, Boopathi, Ettickan, Liu, Yi, Haber, Alex, Ertel, Adam, Bhardwaj, Anshul, Addya, Sankar, Williams, Noelle, Ciment, Stephen J., Cotzia, Paolo, Dean, Jeffry L., Snook, Adam, McNair, Chris, Price, Matt, Hernandez, James R., Zhao, Shuang G., Birbe, Ruth, McCarthy, James B., Turley, Eva A., Pienta, Kenneth J., Feng, Felix Y., Dicker, Adam P., Knudsen, Karen E., Den, Robert B.
Vydáno v Cancer Res (2016)

DNA-PKcs mediated transcriptional regulation drives prostate cancer progression and metastasis

Autor Goodwin, Jonathan F., Kothari, Vishal, Drake, Justin M., Zhao, Shuang, Dylgjeri, Emanuela, Dean, Jeffry L., Schiewer, Matthew J., McNair, Christopher, Jones, Jennifer K., Aytes, Alvaro, Magee, Michael S., Snook, Adam E., Zhu, Ziqi, Den, Robert B., Birbe, Ruth C., Gomella, Leonard G., Graham, Nicholas A., Vashisht, Ajay A., Wohlschlegel, James A., Graeber, Thomas G., Karnes, R. Jeffrey, Takhar, Mandeep, Davicioni, Elai, Tomlins, Scott A., Abate-Shen, Cory, Sharifi, Nima, Witte, Owen N., Feng, Felix Y., Knudsen, Karen E.
Vydáno v Cancer Cell (2015)