Consequence of the tumor-associated conversion to cyclin D1b

Clinical evidence suggests that cyclin D1b, a variant of cyclin D1, is associated with tumor progression and poor outcome. However, the underlying molecular basis was unknown. Here, novel models were created to generate a genetic switch from cyclin D1 to cyclin D1b. Extensive analyses uncovered over...

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Bibliographische Detailangaben
Veröffentlicht in:EMBO Mol Med
Hauptverfasser: Augello, Michael A, Berman-Booty, Lisa D, Carr, Richard, Yoshida, Akihiro, Dean, Jeffry L, Schiewer, Matthew J, Feng, Felix Y, Tomlins, Scott A, Gao, Erhe, Koch, Walter J, Benovic, Jeffrey L, Diehl, John Alan, Knudsen, Karen E
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492821/
https://ncbi.nlm.nih.gov/pubmed/25787974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404242
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