Retinoblastoma tumor suppressor pathway in breast cancer: prognosis, precision medicine, and therapeutic interventions

ανά Witkiewicz, Agnieszka K, Knudsen, Erik S
Έκδοση 2014

Defining the transcriptional and biological response to CDK4/6 inhibition in relation to ER+/HER2- breast cancer

ανά Knudsen, Erik S., Witkiewicz, Agnieszka K.
Τόπος έκδοσης Oncotarget (2016)

The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies

ανά Knudsen, Erik S., Witkiewicz, Agnieszka K.
Τόπος έκδοσης Trends Cancer (2017)

The transcriptome of CDK4/6 inhibition

ανά Knudsen, Erik S., Witkiewicz, Agnieszka K.
Τόπος έκδοσης Aging (Albany NY) (2017)

CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models

ανά Witkiewicz, Agnieszka K., Cox, Derek, Knudsen, Erik S.
Έκδοση 2014

CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer

ανά Franco, Jorge, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Έκδοση 2014

The RB tumor suppressor at the intersection of proliferation and immunity: relevance to disease immune evasion and immunotherapy

ανά Hutcheson, Jack, Witkiewicz, Agnieszka K, Knudsen, Erik S
Τόπος έκδοσης Cell Cycle (2015)

Systematically Defining Single-Gene Determinants of Response to Neoadjuvant Chemotherapy Reveals Specific Biomarkers

ανά Witkiewicz, Agnieszka K., Balaji, Uthra, Knudsen, Erik S.
Τόπος έκδοσης Clin Cancer Res (2014)

Correction: CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models

ανά Witkiewicz, Agnieszka K., Cox, Derek, Knudsen, Erik S.
Τόπος έκδοσης Genes Cancer (2021)

Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature

ανά Knudsen, Erik S., Hutcheson, Jack, Vail, Paris, Witkiewicz, Agnieszka K.
Τόπος έκδοσης Oncotarget (2017)

Coordinately targeting cell cycle checkpoint functions in integrated models of pancreatic cancer

ανά Chung, Sejin, Vail, Paris, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Τόπος έκδοσης Clin Cancer Res (2018)

The history and future of targeting cyclin-dependent kinases in cancer therapy

ανά Asghar, Uzma, Witkiewicz, Agnieszka K., Turner, Nicholas C., Knudsen, Erik S.
Τόπος έκδοσης Nat Rev Drug Discov (2015)

Chemotherapy and CDK4/6 inhibitors: Unexpected bedfellows

ανά Roberts, Patrick J., Kumarasamy, Vishnu, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Τόπος έκδοσης Mol Cancer Ther (2020)

The meaning of p16(ink4a) expression in tumors: Functional significance, clinical associations and future developments

ανά Witkiewicz, Agnieszka K., Knudsen, Karen E., Dicker, Adam P., Knudsen, Erik S.
Έκδοση 2011

A case of endometrial cancer in the context of a BRCA2 mutation and double heterozygosity for Lynch syndrome

ανά Gong, Ping, Charles, Sarah, Rosenblum, Norman, Wang, Zoe, Witkiewicz, Agnieszka K.
Έκδοση 2012

Metabolic re-programming of pancreatic cancer mediated by CDK4/6 inhibition elicits unique vulnerabilities

ανά Franco, Jorge, Balaji, Uthra, Freinkman, Elizaveta, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Τόπος έκδοσης Cell Rep (2016)

Chemotherapy impacts on the cellular response to CDK4/6 inhibition: distinct mechanisms of interaction and efficacy in models of pancreatic cancer

ανά Kumarasamy, Vishnu, Ruiz, Amanda, Nambiar, Ram, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Τόπος έκδοσης Oncogene (2019)

Functional determinants of cell-cycle plasticity and sensitivity to CDK4/6 inhibition

ανά Kumarasamy, Vishnu, Vail, Paris, Nambiar, Ram, Witkiewicz, Agnieszka K, Knudsen, Erik S
Τόπος έκδοσης Cancer Res (2020)

RB Tumor Suppressive Function in Response to Xenobiotic Hepatocarcinogens

ανά Reed, Christopher, Hutcheson, Jack, Mayhew, Christopher N., Witkiewicz, Agnieszka K., Knudsen, Erik S.
Έκδοση 2014

Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision Medicine

ανά Knudsen, Erik S., O’Reilly, Eileen M., Brody, Jonathan R., Witkiewicz, Agnieszka K.
Τόπος έκδοσης Gastroenterology (2015)