Φορτώνει......
Coordinately targeting cell cycle checkpoint functions in integrated models of pancreatic cancer
PURPOSE: Cancer cells often have deficiencies in cell cycle control mechanisms and could be dependent on specific cell cycle checkpoints to maintain viability. Due to the documented role of KRAS in driving replication stress, we targeted the checkpoint governing DNA replication using CHK1 kinase inh...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Clin Cancer Res |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6445724/ https://ncbi.nlm.nih.gov/pubmed/30538111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1620 |
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