Loss of Bim results in abnormal accumulation of mature CD4(-)CD8(-)CD44(-)CD25(-) thymocytes

por Hutcheson, Jack, Perlman, Harris
Publicado em 2007

BH3-only proteins in rheumatoid arthritis: Potential targets for therapeutic intervention

por Hutcheson, Jack, Perlman, Harris
Publicado em 2008

The Role of Cytokines in the Pathogenesis and Treatment of Systemic Lupus Erythematosus

por Davis, Laurie S., Hutcheson, Jack, Mohan, Chandra
Publicado em 2011

The RB tumor suppressor at the intersection of proliferation and immunity: relevance to disease immune evasion and immunotherapy

por Hutcheson, Jack, Witkiewicz, Agnieszka K, Knudsen, Erik S
Publicado no Cell Cycle (2015)

Biological specificity of CDK4/6 inhibitors: dose response relationship, in vivo signaling, and composite response signature

por Knudsen, Erik S., Hutcheson, Jack, Vail, Paris, Witkiewicz, Agnieszka K.
Publicado no Oncotarget (2017)

Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis

por Scatizzi, John C, Hutcheson, Jack, Bickel, Emily, Haines, G Kenneth, Perlman, Harris
Publicado em 2007

RB Tumor Suppressive Function in Response to Xenobiotic Hepatocarcinogens

por Reed, Christopher, Hutcheson, Jack, Mayhew, Christopher N., Witkiewicz, Agnieszka K., Knudsen, Erik S.
Publicado em 2014

Retinoblastoma protein potentiates the innate immune response in hepatocytes: significance to hepatocellular carcinoma

por Hutcheson, Jack, Bourgo, Ryan J., Balaji, Uthra, Ertel, Adam, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Publicado no Hepatology (2014)

Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis

por Hutcheson, Jack, Scatizzi, John C., Bickel, Emily, Brown, Nathaniel J., Bouillet, Philippe, Strasser, Andreas, Perlman, Harris
Publicado em 2005

Curcumin Attenuates Both Acute and Chronic Immune Nephritis

por Wu, Tianfu, Marakkath, Bindiya, Ye, Yujin, Khobahy, Elhaum, Yan, Mei, Hutcheson, Jack, Zhu, Jiankun, Zhou, Xinjin, Mohan, Chandra
Publicado no Int J Mol Sci (2020)

Immunological and Metabolic Features of Pancreatic Ductal Adenocarcinoma Define Prognostic Subtypes of Disease

por Hutcheson, Jack, Balaji, Uthra, Porembka, Matthew R, Wachsmann, Megan B, McCue, Peter A, Knudsen, Erik S, Witkiewicz, Agnieszka K
Publicado no Clin Cancer Res (2016)

p21(Cip1) Is Required for the Development of Monocytes and Their Response to Serum Transfer-induced Arthritis

por Scatizzi, John C., Hutcheson, Jack, Bickel, Emily, Woods, James M., Klosowska, Karolina, Moore, Terry L., Haines, G. Kenneth, Perlman, Harris
Publicado em 2006

Adverse Effects of Simulated Hyper- and Hypo-Phosphatemia on Endothelial Cell Function and Viability

por Peng, Ai, Wu, Tianfu, Zeng, Caihong, Rakheja, Dinesh, Zhu, Jiankun, Ye, Ting, Hutcheson, Jack, Vaziri, Nosratola D., Liu, Zhihong, Mohan, Chandra, Zhou, Xin J.
Publicado em 2011

Myeloid Cell-Specific Fas Expression is Required to Prevent Systemic Autoimmunity

por Cuda, Carla M., Agrawal, Hemant, Misharin, Alexander V., Haines, G. Kenneth, Hutcheson, Jack, Weber, Evan, Schoenfeldt, JA, Mohan, Chandra, Pope, Richard M., Perlman, Harris
Publicado em 2012

Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus

por Hutcheson, Jack, Vanarsa, Kamala, Bashmakov, Anna, Grewal, Simer, Sajitharan, Deena, Chang, Betty Y, Buggy, Joseph J, Zhou, Xin J, Du, Yong, Satterthwaite, Anne B, Mohan, Chandra
Publicado em 2012

Bim-BH3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

por Scatizzi, John C., Hutcheson, Jack, Pope, Richard M., Firestein, Gary S., Koch, Alisa E., Mavers, Melissa, Smason, Avraham, Agrawal, Hemant, Haines, G. Kenneth, Chandel, Navdeep S., Hotchkiss, Richard S., Perlman, Harris
Publicado em 2010

Caspase-8 Acts as a Molecular Rheostat to Limit RIPK1- and MyD88-Mediated Dendritic Cell Activation()

por Cuda, Carla M., Misharin, Alexander V., Gierut, Angelica K., Saber, Rana, Haines, G. Kenneth, Hutcheson, Jack, Hedrick, Stephen M., Mohan, Chandra, Budinger, G. Scott, Stehlik, Christian, Perlman, Harris
Publicado em 2014

The cyclin dependent kinase domain of p21 is a suppressor of IL-1β-mediated inflammation in activated macrophages

por Scatizzi, John C., Mavers, Melissa, Hutcheson, Jack, Young, Brittany, Shi, Bo, Pope, Richard M., Ruderman, Eric M., Samways, Damien S.K., Corbett, John A., Egan, Terrance M., Perlman, Harris
Publicado em 2009

Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE

por Orme, Jacob J., Du, Yong, Vanarsa, Kamala, Mayeux, Jessica, Li, Li, Mutwally, Azza, Arriens, Cristina, Min, Soyoun, Hutcheson, Jack, Davis, Laurie S., Chong, Benjamin F., Satterthwaite, Anne B., Wu, Tianfu, Mohan, Chandra
Publicado no Clin Immunol (2016)

Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner

por Cuda, Carla M., Misharin, Alexander V., Khare, Sonal, Saber, Rana, Tsai, FuNien, Archer, Amy M., Homan, Philip J., Haines, G. Kenneth, Hutcheson, Jack, Dorfleutner, Andrea, Budinger, G. R. Scott, Stehlik, Christian, Perlman, Harris
Publicado no Arthritis Res Ther (2015)