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Retinoblastoma protein potentiates the innate immune response in hepatocytes: significance to hepatocellular carcinoma

Cancers mediated by viral etiology must exhibit deregulated cellular proliferation and evade immune recognition. The role of the retinoblastoma tumor suppressor (RB) pathway, which is lost at relatively high frequency in HCC, has recently been expanded to include the regulation of innate immune resp...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Hutcheson, Jack, Bourgo, Ryan J., Balaji, Uthra, Ertel, Adam, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482134/
https://ncbi.nlm.nih.gov/pubmed/24824777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27217
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