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Immunological and Metabolic Features of Pancreatic Ductal Adenocarcinoma Define Prognostic Subtypes of Disease

PURPOSE: Pancreatic ductal adenocarcinoma (PDA) is associated with an immunosuppressive microenvironment that supports the growth of the malignancy as well as immune system evasion. Here we examine markers of immunosuppression in PDA within the context of the glycolytic tumor microenvironment, their...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Hutcheson, Jack, Balaji, Uthra, Porembka, Matthew R, Wachsmann, Megan B, McCue, Peter A, Knudsen, Erik S, Witkiewicz, Agnieszka K
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947442/
https://ncbi.nlm.nih.gov/pubmed/26858311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1883
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