Immunological and Metabolic Features of Pancreatic Ductal Adenocarcinoma Define Prognostic Subtypes of Disease

PURPOSE: Pancreatic ductal adenocarcinoma (PDA) is associated with an immunosuppressive microenvironment that supports the growth of the malignancy as well as immune system evasion. Here we examine markers of immunosuppression in PDA within the context of the glycolytic tumor microenvironment, their...

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Bibliographic Details
Published in:Clin Cancer Res
Main Authors: Hutcheson, Jack, Balaji, Uthra, Porembka, Matthew R, Wachsmann, Megan B, McCue, Peter A, Knudsen, Erik S, Witkiewicz, Agnieszka K
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947442/
https://ncbi.nlm.nih.gov/pubmed/26858311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1883
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