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Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The aggressiveness and therapeutic recalcitrance of this malignancy has been attributed to multiple factors including the influence of an active desmoplastic stroma. How the stromal microenvironment of PDAC contributes to the fatal natu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Knudsen, Erik S., Balaji, Uthra, Freinkman, Elizaveta, McCue, Peter, Witkiewicz, Agnieszka K.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346648/
https://ncbi.nlm.nih.gov/pubmed/27623078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11893
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