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Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potential

Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis. The aggressiveness and therapeutic recalcitrance of this malignancy has been attributed to multiple factors including the influence of an active desmoplastic stroma. How the stromal microenvironment of PDAC contributes to the fatal natu...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Knudsen, Erik S., Balaji, Uthra, Freinkman, Elizaveta, McCue, Peter, Witkiewicz, Agnieszka K.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346648/
https://ncbi.nlm.nih.gov/pubmed/27623078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11893
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