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Caspase-8 Acts as a Molecular Rheostat to Limit RIPK1- and MyD88-Mediated Dendritic Cell Activation()
Caspase-8, an executioner enzyme in the death receptor pathway, has previously been shown to initiate apoptosis and suppress necroptosis. Here, we identify a novel, cell death-independent role for caspase-8 in dendritic cells (DCs); namely, DC-specific expression of caspase-8 prevents the onset of s...
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| Главные авторы: | , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074511/ https://ncbi.nlm.nih.gov/pubmed/24808358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400122 |
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