Caspase-8 Acts as a Molecular Rheostat to Limit RIPK1- and MyD88-Mediated Dendritic Cell Activation()

Caspase-8, an executioner enzyme in the death receptor pathway, has previously been shown to initiate apoptosis and suppress necroptosis. Here, we identify a novel, cell death-independent role for caspase-8 in dendritic cells (DCs); namely, DC-specific expression of caspase-8 prevents the onset of s...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Cuda, Carla M., Misharin, Alexander V., Gierut, Angelica K., Saber, Rana, Haines, G. Kenneth, Hutcheson, Jack, Hedrick, Stephen M., Mohan, Chandra, Budinger, G. Scott, Stehlik, Christian, Perlman, Harris
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074511/
https://ncbi.nlm.nih.gov/pubmed/24808358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400122
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky