Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner

INTRODUCTION: Although caspase-8 is a well-established initiator of apoptosis and suppressor of necroptosis, recent evidence suggests that this enzyme maintains functions beyond its role in cell death. As cells of the innate immune system, and in particular macrophages, are now at the forefront of a...

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Bibliografske podrobnosti
izdano v:Arthritis Res Ther
Main Authors: Cuda, Carla M., Misharin, Alexander V., Khare, Sonal, Saber, Rana, Tsai, FuNien, Archer, Amy M., Homan, Philip J., Haines, G. Kenneth, Hutcheson, Jack, Dorfleutner, Andrea, Budinger, G. R. Scott, Stehlik, Christian, Perlman, Harris
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608154/
https://ncbi.nlm.nih.gov/pubmed/26471282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0794-z
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