Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner

INTRODUCTION: Although caspase-8 is a well-established initiator of apoptosis and suppressor of necroptosis, recent evidence suggests that this enzyme maintains functions beyond its role in cell death. As cells of the innate immune system, and in particular macrophages, are now at the forefront of a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Cuda, Carla M., Misharin, Alexander V., Khare, Sonal, Saber, Rana, Tsai, FuNien, Archer, Amy M., Homan, Philip J., Haines, G. Kenneth, Hutcheson, Jack, Dorfleutner, Andrea, Budinger, G. R. Scott, Stehlik, Christian, Perlman, Harris
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608154/
https://ncbi.nlm.nih.gov/pubmed/26471282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0794-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados