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The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response

BACKGROUND: Caspase-8 is a well-established initiator of apoptosis and suppressor of necroptosis, but maintains functions beyond cell death that involve suppression of receptor-interacting serine-threonine kinases (RIPKs). A genome-wide association study meta-analysis revealed an SNP associated with...

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Bibliografske podrobnosti
izdano v:Arthritis Res Ther
Main Authors: Dominguez, Salina, Montgomery, Anna B., Haines, G. Kenneth, Bloomfield, Christina L., Cuda, Carla M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5628498/
https://ncbi.nlm.nih.gov/pubmed/28978351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-017-1436-4
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