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Myeloid Cell-Specific Fas Expression is Required to Prevent Systemic Autoimmunity
OBJECTIVE: The death receptor Fas is a critical mediator of the extrinsic apoptotic pathway. While the role that Fas plays in mediating lymphoproliferation has been extensively investigated, the impact of myeloid cell-specific loss of Fas has yet to be examined. METHODS: Mice with Fas flanked by lox...
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| Glavni autori: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3290732/ https://ncbi.nlm.nih.gov/pubmed/22143975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34317 |
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