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The Cyclin Dependent Kinase Inhibitor p21 Is Essential for Resolution of Murine Inflammatory Arthritis via its C-Terminal Domain
OBJECTIVE: The mechanism responsible for persistent inflammation of the synovium that occurs in patients with rheumatoid arthritis (RA) is unknown. Previously, we were the first to demonstrate that expression of the cyclin dependent kinase (CDK) inhibitor p21((WAF1/CIP1)) is reduced in synovial tiss...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253189/ https://ncbi.nlm.nih.gov/pubmed/21898359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33311 |
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