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Bim-BH3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis

OBJECTIVE: Rheumatoid arthritis (RA) is a destructive autoimmune disease characterized by an increased inflammation in the joint. Therapies which activate the apoptotic cascade may have potential as a future therapy for RA, however few therapeutics fit this category. Recently, therapies that mimic t...

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Detalhes bibliográficos
Main Authors: Scatizzi, John C., Hutcheson, Jack, Pope, Richard M., Firestein, Gary S., Koch, Alisa E., Mavers, Melissa, Smason, Avraham, Agrawal, Hemant, Haines, G. Kenneth, Chandel, Navdeep S., Hotchkiss, Richard S., Perlman, Harris
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848986/
https://ncbi.nlm.nih.gov/pubmed/20112357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27198
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