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Loss of Bim results in abnormal accumulation of mature CD4(-)CD8(-)CD44(-)CD25(-) thymocytes
The process of thymopoiesis is tightly regulated by a series of selection events which ensure that only functional T-lymphocytes directed against foreign antigens are exported into the periphery. The adaptive immune response largely depends on the regulation of thymocyte development, and thymocytes...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2074878/ https://ncbi.nlm.nih.gov/pubmed/17869640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2007.05.003 |
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