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Notch1 Signaling Promotes the Maturation of CD4 and CD8 SP Thymocytes
Notch proteins regulate many developmental processes. Notch1 is highly expressed on thymocytes, but its role in regulating their development is not known. We show that activation of Notch1 signaling in CD4(+)CD8(+) double positive thymocytes promotes the maturation of both CD4(+) and CD8(+) single p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2780426/ https://ncbi.nlm.nih.gov/pubmed/10933396 |
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