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Immature single-positive CD8(+) thymocytes represent the transition from Notch-dependent to Notch-independent T-cell development

Early in T-cell development, cells proceed through stages that are critically dependent on signaling through the Notch receptor. As cells mature, thymocytes transition from being Notch dependent to being Notch independent, but the stage of development during which this transition occurs is unknown....

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Detalhes bibliográficos
Main Authors: Xiong, Juan, Armato, Michael A., Yankee, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031305/
https://ncbi.nlm.nih.gov/pubmed/21148236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq457
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