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Immature single-positive CD8(+) thymocytes represent the transition from Notch-dependent to Notch-independent T-cell development

Early in T-cell development, cells proceed through stages that are critically dependent on signaling through the Notch receptor. As cells mature, thymocytes transition from being Notch dependent to being Notch independent, but the stage of development during which this transition occurs is unknown....

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Autori principali: Xiong, Juan, Armato, Michael A., Yankee, Thomas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031305/
https://ncbi.nlm.nih.gov/pubmed/21148236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq457
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