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Immature single-positive CD8(+) thymocytes represent the transition from Notch-dependent to Notch-independent T-cell development
Early in T-cell development, cells proceed through stages that are critically dependent on signaling through the Notch receptor. As cells mature, thymocytes transition from being Notch dependent to being Notch independent, but the stage of development during which this transition occurs is unknown....
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Oxford University Press
2011
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Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3031305/ https://ncbi.nlm.nih.gov/pubmed/21148236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq457 |
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