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Gads-deficient thymocytes are blocked at the transitional single positive CD4(+) stage

Positive selection of T cell precursors is the process by which a diverse T cell repertoire is established. Positive selection begins at the CD4(+)CD8(+) double positive (DP) stage of development and involves at least two steps. First, DP thymocytes downregulate CD8 to become transitional single pos...

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Detalhes bibliográficos
Main Authors: Dalheimer, Stacy L., Zeng, Ling, Draves, Kevin E., Hassaballa, Ashraf, Jiwa, Nasheena N., Parrish, Torrey D., Clark, Edward A., Yankee, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768049/
https://ncbi.nlm.nih.gov/pubmed/19337995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838692
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