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Gads-deficient thymocytes are blocked at the transitional single positive CD4(+) stage
Positive selection of T cell precursors is the process by which a diverse T cell repertoire is established. Positive selection begins at the CD4(+)CD8(+) double positive (DP) stage of development and involves at least two steps. First, DP thymocytes downregulate CD8 to become transitional single pos...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768049/ https://ncbi.nlm.nih.gov/pubmed/19337995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838692 |
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