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Gads regulates the expansion phase of CD8(+) T cell-mediated immunity()

The Gads adaptor protein is critical for TCR-mediated Ca(2+) mobilization. We investigated the effect of Gads deficiency on the proliferation of CD8(+) T cells following peptide stimulation and in the context of infection with an intracellular pathogen. We stimulated CD8(+) T cells from Gads(+/+) OT...

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Autori principali: Zhang, Elizabeth Yan, Parker, Brooks L., Yankee, Thomas M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368553/
https://ncbi.nlm.nih.gov/pubmed/21411729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001604
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