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Maternal PD-1 Regulates Accumulation of Fetal Antigen-Specific CD8(+) T cells in Pregnancy
The failure to reject the semi-allogeneic fetus suggests that maternal T lymphocytes are regulated by potent mechanisms in pregnancy. The T cell immunoinhibitory receptor, Programmed Death-1 (PD-1), and its ligand, B7-H1, maintain peripheral tolerance by inhibiting activation of self-reactive lympho...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764286/ https://ncbi.nlm.nih.gov/pubmed/19368976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jri.2008.12.001 |
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