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Chemotherapy and CDK4/6 inhibitors: Unexpected bedfellows

Cyclin-dependent kinases 4 and 6 (CDK4/6) have emerged as important therapeutic targets. Pharmacological inhibitors of these kinases function to inhibit cell cycle progression and exert other important effects on the tumor and host environment. Due to their impact on the cell cycle, CDK4/6 inhibitor...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Roberts, Patrick J., Kumarasamy, Vishnu, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473501/
https://ncbi.nlm.nih.gov/pubmed/32546660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-1161
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