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Chemotherapy and CDK4/6 inhibitors: Unexpected bedfellows

Cyclin-dependent kinases 4 and 6 (CDK4/6) have emerged as important therapeutic targets. Pharmacological inhibitors of these kinases function to inhibit cell cycle progression and exert other important effects on the tumor and host environment. Due to their impact on the cell cycle, CDK4/6 inhibitor...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Ther
Main Authors: Roberts, Patrick J., Kumarasamy, Vishnu, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473501/
https://ncbi.nlm.nih.gov/pubmed/32546660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-1161
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