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Chemotherapy and CDK4/6 inhibitors: Unexpected bedfellows

Cyclin-dependent kinases 4 and 6 (CDK4/6) have emerged as important therapeutic targets. Pharmacological inhibitors of these kinases function to inhibit cell cycle progression and exert other important effects on the tumor and host environment. Due to their impact on the cell cycle, CDK4/6 inhibitor...

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Podrobná bibliografie
Vydáno v:Mol Cancer Ther
Hlavní autoři: Roberts, Patrick J., Kumarasamy, Vishnu, Witkiewicz, Agnieszka K., Knudsen, Erik S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7473501/
https://ncbi.nlm.nih.gov/pubmed/32546660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-1161
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