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The history and future of targeting cyclin-dependent kinases in cancer therapy
Cancer represents a pathological manifestation of uncontrolled cell division; therefore, it has long been anticipated that our understanding of the basic principles of cell cycle control would result in effective cancer therapies. In particular, cyclin-dependent kinases (CDKs) that promote transitio...
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| Publicado no: | Nat Rev Drug Discov |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4480421/ https://ncbi.nlm.nih.gov/pubmed/25633797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd4504 |
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