RB Loss Promotes Prostate Cancer Metastasis

RB loss occurs commonly in neoplasia but its contributions to advanced cancer have not been assessed directly. Here we show that RB loss in multiple murine models of cancer produces a prometastatic phenotype. Gene expression analyses showed that regulation of the cell motility receptor RHAMM by the...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Thangavel, Chellappagounder, Boopathi, Ettickan, Liu, Yi, Haber, Alex, Ertel, Adam, Bhardwaj, Anshul, Addya, Sankar, Williams, Noelle, Ciment, Stephen J., Cotzia, Paolo, Dean, Jeffry L., Snook, Adam, McNair, Chris, Price, Matt, Hernandez, James R., Zhao, Shuang G., Birbe, Ruth, McCarthy, James B., Turley, Eva A., Pienta, Kenneth J., Feng, Felix Y., Dicker, Adam P., Knudsen, Karen E., Den, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700768/
https://ncbi.nlm.nih.gov/pubmed/27923835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1589
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