The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness

PURPOSE: Perturbations in the RB pathway are overrepresented in advanced prostate cancer; RB loss promotes bypass of first line hormone therapy. Conversely, preliminary studies suggested that RB-deficient tumors may become sensitized to a subset of DNA damaging agents. Here, the molecular and in viv...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Thangavel, Chellappagounder, Boopathi, Ettickan, Ciment, Steve, Liu, Yi, O’Neill, Raymond, Sharma, Ankur, McMahon, Steve B., Mellert, Hestia, Addya, Sankar, Ertel, Adam, Birbe, Ruth, Fortina, Paolo, Dicker, Adam P, Knudsen, Karen E, Den, Robert B
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4216759/
https://ncbi.nlm.nih.gov/pubmed/25165096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0326
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