AMPed up to treat prostate cancer: novel AMPK activators emerge for cancer therapy

Por Schiewer, Matthew J, Knudsen, Karen E
Publicado em 2014

Transcriptional roles of PARP-1 in cancer

Por Schiewer, Matthew J., Knudsen, Karen E.
Publicado em 2014

Linking DNA damage and hormone signaling pathways in cancer

Por Schiewer, Matthew J., Knudsen, Karen E.
Publicado no Trends Endocrinol Metab (2016)

The AR dependent cell cycle: Mechanisms and cancer relevance

Por Schiewer, Matthew J., Augello, Michael A., Knudsen, Karen E.
Publicado em 2011

Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression

Por Schrecengost, Randy S., Keller, Staci N., Schiewer, Matthew J., Knudsen, Karen E., Smith, Charles D.
Publicado no Mol Cancer Res (2015)

mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer

Por Schiewer, Matthew J, Den, Robert, Hoang, David T, Augello, Michael A, Lawrence, Yaacov R, Dicker, Adam P, Knudsen, Karen E
Publicado em 2012

Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer

Por Schiewer, Matthew J., Morey, Lisa M., Burd, Craig J., Liu, Yuhong, Merry, Diane E., Ho, Shuk-Mei, Knudsen, Karen E.
Publicado em 2008

Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene

Por Olshavsky, Nicholas A., Comstock, Clay E.S., Schiewer, Matthew J., Augello, Michael A., Hyslop, Terry, Sette, Claudio, Zhang, Jinsong, Parysek, Linda M., Knudsen, Karen E.
Publicado em 2010

Progesterone Receptor–Cyclin D1 Complexes Induce Cell Cycle–Dependent Transcriptional Programs in Breast Cancer Cells

Por Dressing, Gwen E., Knutson, Todd P., Schiewer, Matthew J., Daniel, Andrea R., Hagan, Christy R., Diep, Caroline H., Knudsen, Karen E., Lange, Carol A.
Publicado em 2014

Cyclin D1 Is a Selective Modifier of Androgen-dependent Signaling and Androgen Receptor Function

Por Comstock, Clay E. S., Augello, Michael A., Schiewer, Matthew J., Karch, Jason, Burd, Craig J., Ertel, Adam, Knudsen, Erik S., Jessen, Walter J., Aronow, Bruce J., Knudsen, Karen E.
Publicado em 2011

A hormone-DNA repair circuit governs the response to genotoxic insult

Por Goodwin, Jonathan F., Schiewer, Matthew J., Dean, Jeffry L., Schrecengost, Randy S., de Leeuw, Renee, Han, Sumin, Ma, Teng, Den, Robert B., Dicker, Adam P., Feng, Felix Y., Knudsen, Karen E.
Publicado em 2013

Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer

Por Steffen, Jamin D., Tholey, Renee M., Langelier, Marie-France, Planck, Jamie L., Schiewer, Matthew J., Lal, Shruti, Bildzukewicz, Nikolai A., Yeo, Charles J., Knudsen, Karen E., Brody, Jonathan R., Pascal, John M.
Publicado em 2013

Novel actions of next-generation taxanes benefit advanced stages of prostate cancer

Por de Leeuw, Renée, Berman-Booty, Lisa D, Schiewer, Matthew J, Ciment, Stephen J, Den, Robert B, Dicker, Adam P, Kelly, William K, Trabulsi, Edouard J, Lallas, Costas D, Gomella, Leonard G, Knudsen, Karen E
Publicado no Clin Cancer Res (2015)

Consequence of the tumor-associated conversion to cyclin D1b

Por Augello, Michael A, Berman-Booty, Lisa D, Carr, Richard, Yoshida, Akihiro, Dean, Jeffry L, Schiewer, Matthew J, Feng, Felix Y, Tomlins, Scott A, Gao, Erhe, Koch, Walter J, Benovic, Jeffrey L, Diehl, John Alan, Knudsen, Karen E
Publicado no EMBO Mol Med (2015)

USP22 Regulates Oncogenic Signaling Pathways to Drive Lethal Cancer Progression

Por Schrecengost, Randy S, Dean, Jeffry L, Goodwin, Jonathan F, Schiewer, Matthew J, Urban, Mark W, Stanek, Timothy J, Sussman, Robyn T, Hicks, Jessica L, Birbe, Ruth C, Draganova-Tacheva, Rossitza A, Visakorpi, Tapio, DeMarzo, Angelo M, McMahon, Steven B, Knudsen, Karen E
Publicado em 2013

Dual roles of PARP-1 promote cancer growth and progression

Por Schiewer, Matthew J., Goodwin, Jonathan F., Han, Sumin, Brenner, J. Chad, Augello, Michael A., Dean, Jeffry L., Liu, Fengzhi, Planck, Jamie L., Ravindranathan, Preethi, Chinnaiyan, Arul M., McCue, Peter, Gomella, Leonard G., Raj, Ganesh V., Dicker, Adam P., Brody, Jonathan R., Pascal, John M., Centenera, Margaret M., Butler, Lisa M., Tilley, Wayne D., Feng, Felix Y., Knudsen, Karen E.
Publicado em 2012

DNA-PKcs mediated transcriptional regulation drives prostate cancer progression and metastasis

Por Goodwin, Jonathan F., Kothari, Vishal, Drake, Justin M., Zhao, Shuang, Dylgjeri, Emanuela, Dean, Jeffry L., Schiewer, Matthew J., McNair, Christopher, Jones, Jennifer K., Aytes, Alvaro, Magee, Michael S., Snook, Adam E., Zhu, Ziqi, Den, Robert B., Birbe, Ruth C., Gomella, Leonard G., Graham, Nicholas A., Vashisht, Ajay A., Wohlschlegel, James A., Graeber, Thomas G., Karnes, R. Jeffrey, Takhar, Mandeep, Davicioni, Elai, Tomlins, Scott A., Abate-Shen, Cory, Sharifi, Nima, Witte, Owen N., Feng, Felix Y., Knudsen, Karen E.
Publicado no Cancer Cell (2015)