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Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer
Regulation of the androgen receptor (AR) is critical to prostate cancer (PCa) development; therefore, AR is the first line therapeutic target for disseminated tumors. Cell cycle dependent accumulation of cyclin D1 negatively modulates the transcriptional regulation of the AR through discrete, CDK4-i...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852245/ https://ncbi.nlm.nih.gov/pubmed/19079343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.446 |
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