Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer

Regulation of the androgen receptor (AR) is critical to prostate cancer (PCa) development; therefore, AR is the first line therapeutic target for disseminated tumors. Cell cycle dependent accumulation of cyclin D1 negatively modulates the transcriptional regulation of the AR through discrete, CDK4-i...

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Hlavní autoři: Schiewer, Matthew J., Morey, Lisa M., Burd, Craig J., Liu, Yuhong, Merry, Diane E., Ho, Shuk-Mei, Knudsen, Karen E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852245/
https://ncbi.nlm.nih.gov/pubmed/19079343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.446
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