Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation

Cyclin D1 is a multifaceted regulator of both transcription and cell-cycle progression that exists in two distinct isoforms, cyclin D1a and D1b. In the prostate, cyclin D1a acts through discrete mechanisms to negatively regulate androgen receptor (AR) activity and thus limit androgen-dependent proli...

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Detalhes bibliográficos
Main Authors: Burd, Craig J., Petre, Christin E., Morey, Lisa M., Wang, Ying, Revelo, Monica P., Haiman, Christopher A., Lu, Shan, Fenoglio-Preiser, Cecilia M., Li, Jiwen, Knudsen, Erik S., Wong, Jiemin, Knudsen, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413684/
https://ncbi.nlm.nih.gov/pubmed/16461912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506281103
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