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Outsmarting androgen receptor: creative approaches for targeting aberrant androgen signaling in advanced prostate cancer

Prostatic adenocarcinomas are reliant on androgen receptor (AR) activity for survival and progression. Therefore, first-line therapeutic intervention for disseminated disease entails the use of AR-directed therapeutics, achieved through androgen deprivation and direct AR antagonists. While initially...

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Detalhes bibliográficos
Main Authors: Knudsen, Karen E, Kelly, William Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289283/
https://ncbi.nlm.nih.gov/pubmed/22389648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/eem.11.33
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