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Targeting Androgen Receptor Aberrations in Castration-Resistant Prostate Cancer

Androgen receptor (AR) splice variants (SV) have been implicated in the development of metastatic castration-resistant prostate cancer and resistance to AR targeting therapies, including abiraterone and enzalutamide. Agents targeting AR-SV are urgently needed to test this hypothesis and further impr...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Sharp, Adam, Welti, Jonathan, Blagg, Julian, de Bono, Johann S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302169/
https://ncbi.nlm.nih.gov/pubmed/27330057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1137
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