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Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene

The cyclin D1b oncogene arises from alternative splicing of the CCND1 transcript, and harbors markedly enhanced oncogenic functions not shared by full-length cyclin D1 (cyclin D1a). Recent studies showed that cyclin D1b is selectively induced in a subset of tissues as a function of tumorigenesis; ho...

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Detalhes bibliográficos
Main Authors: Olshavsky, Nicholas A., Comstock, Clay E.S., Schiewer, Matthew J., Augello, Michael A., Hyslop, Terry, Sette, Claudio, Zhang, Jinsong, Parysek, Linda M., Knudsen, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873684/
https://ncbi.nlm.nih.gov/pubmed/20460515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3468
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