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The gene encoding the splicing factor SF2/ASF is a proto-oncogene

Alternative splicing modulates the expression of many oncogene and tumor-suppressor isoforms. We have tested whether some alternative splicing factors are involved in cancer. We found that the splicing factor SF2/ASF is upregulated in various human tumors, in part due to amplification of its gene, S...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Karni, Rotem, de Stanchina, Elisa, Lowe, Scott W, Sinha, Rahul, Mu, David, Krainer, Adrian R
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4595851/
https://ncbi.nlm.nih.gov/pubmed/17310252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1209
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