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Deletion of the N-terminus of SF2/ASF Permits RS-Domain-Independent Pre-mRNA Splicing
Serine/arginine-rich (SR) proteins are essential splicing factors with one or two RNA-recognition motifs (RRMs) and a C-terminal arginine- and serine-rich (RS) domain. SR proteins bind to exonic splicing enhancers via their RRM(s), and from this position are thought to promote splicing by antagonizi...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1952110/ https://ncbi.nlm.nih.gov/pubmed/17786225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000854 |
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