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SF2/ASF Autoregulation Involves Multiple Layers of Post-transcriptional and Translational Control

SF2/ASF is a prototypical SR protein, with important roles in splicing and other aspects of mRNA metabolism. SFRS1 (SF2/ASF) is a potent proto-oncogene with abnormal expression in many tumors. We found that SF2/ASF negatively autoregulates its expression to maintain homeostatic levels. We characteri...

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Detalhes bibliográficos
Main Authors: Sun, Shuying, Zhang, Zuo, Sinha, Rahul, Karni, Rotem, Krainer, Adrian R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921916/
https://ncbi.nlm.nih.gov/pubmed/20139984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1750
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