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SF2/ASF Autoregulation Involves Multiple Layers of Post-transcriptional and Translational Control
SF2/ASF is a prototypical SR protein, with important roles in splicing and other aspects of mRNA metabolism. SFRS1 (SF2/ASF) is a potent proto-oncogene with abnormal expression in many tumors. We found that SF2/ASF negatively autoregulates its expression to maintain homeostatic levels. We characteri...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2921916/ https://ncbi.nlm.nih.gov/pubmed/20139984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1750 |
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