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Linking DNA damage and hormone signaling pathways in cancer

DNA damage response and repair (DDR) is a tightly controlled process that serves as a barrier to tumorigenesis. Consequently, DDR is frequently altered in human malignancy, and can be exploited for therapeutic gain either through molecularly targeted therapies, or as a consequence of therapeutic age...

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Publicat a:Trends Endocrinol Metab
Autors principals: Schiewer, Matthew J., Knudsen, Karen E.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808434/
https://ncbi.nlm.nih.gov/pubmed/26944914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2016.02.004
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