Patient-derived Models Reveal Impact of the Tumor Microenvironment on Therapeutic Response

BACKGROUND: Androgen deprivation therapy is a first-line treatment for disseminated prostate cancer (PCa). However, virtually all tumors become resistant and recur as castration-resistant PCa, which has no durable cure. One major hurdle in the development of more effective therapies is the lack of p...

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Gepubliceerd in:Eur Urol Oncol
Hoofdauteurs: Shafi, Ayesha A., Schiewer, Matthew J., de Leeuw, Renée, Dylgjeri, Emanuela, McCue, Peter A., Shah, Neelima, Gomella, Leonard G., Lallas, Costas D., Trabulsi, Edouard J., Centenera, Margaret M., Hickey, Theresa E., Butler, Lisa M., Raj, Ganesh, Tilley, Wayne D., Cukierman, Edna, Knudsen, Karen E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6241309/
https://ncbi.nlm.nih.gov/pubmed/30467556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euo.2018.04.019
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