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Modification of the DNA Damage Response by Therapeutic CDK4/6 Inhibition
The RB/E2F axis represents a critical node of cell signaling that integrates a diverse array of signaling pathways. Recent evidence has suggested a role for E2F-mediated gene transcription in DNA damage response and repair, as well as apoptosis signaling. Herein, we investigated how repression of E2...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436568/ https://ncbi.nlm.nih.gov/pubmed/22733811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365494 |
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