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Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors
To model the heterogeneity of breast cancer as observed in the clinic, we employed an ex vivo model of breast tumor tissue. This methodology maintained the histological integrity of the tumor tissue in unselected breast cancers, and importantly, the explants retained key molecular markers that are c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409015/ https://ncbi.nlm.nih.gov/pubmed/22767154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21195 |
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