Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors

To model the heterogeneity of breast cancer as observed in the clinic, we employed an ex vivo model of breast tumor tissue. This methodology maintained the histological integrity of the tumor tissue in unselected breast cancers, and importantly, the explants retained key molecular markers that are c...

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Bibliografske podrobnosti
Main Authors: Dean, Jeffry L., McClendon, A. Kathleen, Hickey, Theresa E., Butler, Lisa M., Tilley, Wayne D., Witkiewicz, Agnieszka K., Knudsen, Erik S.
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409015/
https://ncbi.nlm.nih.gov/pubmed/22767154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21195
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