RB-pathway disruption in breast cancer: Differential association with disease subtypes, disease-specific prognosis and therapeutic response

In breast cancer, inactivation of the RB tumor suppressor gene is believed to occur via multiple mechanisms to facilitate tumorigenesis. However, the prognostic and predictive value of RB status in disease-specific clinical outcomes has remained uncertain. We investigated RB pathway deregulation in...

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Huvudupphovsmän: Ertel, Adam, Dean, Jeffry L, Rui, Hallgeir, Liu, Chengbao, Witkiewicz, Agnes K, Knudsen, Karen E, Knudsen, Erik S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2010
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Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055199/
https://ncbi.nlm.nih.gov/pubmed/20948315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.9.20.13454
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