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Tailoring to RB: tumour suppressor status and therapeutic response
The retinoblastoma tumour suppressor (RB) is a crucial regulator of cell-cycle progression that is invoked in response to a myriad of anti-mitogenic signals. It has been hypothesized that perturbations of the RB pathway confer a synonymous proliferative advantage to tumour cells; however, recent fin...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914856/ https://ncbi.nlm.nih.gov/pubmed/19143056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc2401 |
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